Risk of Prostate Cancer in US Veterans With Rheumatoid Arthritis
Main finding · Prostate cancerResult — go to the resultAdjusted hazard ratio 1.12 95% CI 1.04–1.20Authors' conclusion
RA was associated with a modestly increased risk of prostate cancer, but not prostate cancer mortality, after accounting for relevant confounders and several potential sources of bias.
Study context
- Population
- Male patients with and without rheumatoid arthritis (RA) in the Veterans Health Administration, 2000 to 20182,337,104 patient-years
- Exposure
- Male veterans with RA vs matched veterans without RA
- Outcome
- Prostate cancer risk
Methodological detailsmatched (up to 1:5), multivariable Cox models, models accounting for retention in the VA system
- Matched (up to 1:5)
- Multivariable Cox models
- Models accounting for retention in the VA system
Main finding
Prostate cancer
Adjusted hazard ratio
1.12
95% CI 1.04–1.20
By group
RAvs Without RA
aHR 1.12 (95% CI 1.04–1.20)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | aHR (95% CI) | |
|---|---|---|
| Prostate cancer mortalityRAvs Without RA | 0.92 (0.73–1.16) | |
| 0.512Adjusted hazard ratio (log scale) |
Prostate cancer mortality
- No association between RA and prostate cancer mortality
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Risk of Prostate Cancer in US Veterans With Rheumatoid Arthritis. Arthritis Care Res (Hoboken). Published 18 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →