Associations of Frailty With the Risk of Incident Cancer and Cancer‐Related Mortality in Veterans With Rheumatoid Arthritis
Authors' conclusion
Frailty was independently associated with increased cancer incidence in RA
Study context
- Population
- Veterans with rheumatoid arthritis (RA), Veterans' Affairs Rheumatoid Arthritis Registry (2002–2023) (mean age 63.8 ± 11.2 years; 87.6% male; 15.4% Black)
- Participants
- 2,723 veterans
- Exposure
- Prefrail and frail vs robust in RA
- Outcome
- Cancer incidence
Methodological detailscompeting risk models, fully adjusted models
- Competing risk models
- Fully adjusted models
Main finding
As reported in the abstract
Each group vs robustSubdistribution hazard ratio (95% CI)
Prefrail
1.37(1.02–1.84)
Frail
1.83(1.23–2.71)
Observational data: associations, not effects.
Further findings
Cancer-related mortality
Cancer-related mortality
- No significant associations for overall frailty
Domain-specific and sensitivity analyses
- Consistent with main findings
Original publication
Associations of Frailty With the Risk of Incident Cancer and Cancer‐Related Mortality in Veterans With Rheumatoid Arthritis. Arthritis Care Res (Hoboken). Published 26 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →