Spondyloarthritis & psoriatic arthritis

Risk of Mortality of People With Psoriasis and Psoriatic Arthritis in Taiwan: A Nationwide Cohort Study

J RheumatolPublished Retrospective cohort study

Main finding · All-cause mortality, after PSMResult — go to the resultAdjusted hazard ratio 1.20 95% CI 1.16–1.24

Authors' conclusion

There was an increased risk of all-cause mortality in individuals with PsD compared to individuals without PsD before and after both PSM and adjustment for comorbidities.

Study context

Population
Nationwide population-based insurance claim datasets, Taiwan, 2010–2018: patients with incident psoriatic disease (PsD) (40.2% women) and propensity score matching (PSM) non-PsD individualsequal number of PSM controls
Exposure
Incident psoriatic disease vs PSM non-PsD individuals
  • PsDn = 108,642
Outcome
All-cause mortality
Methodological detailsnationwide, population-based, propensity score matching, Cox regression
  • Nationwide
  • Population-based
  • Propensity score matching
  • Cox regression

Main finding

All-cause mortality, after PSM

Adjusted hazard ratio

1.20

95% CI 1.16–1.24

PsDvs Non-PsD
aHR 1.20 (95% CI 1.16–1.24)

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeaHR (95% CI)P value
All-cause mortalityvs age- and sex-matched controlsAge- and sex-matched controls1.73 (1.68–1.77)P < 0.001

Mortality by biologic therapy exposure and psoriatic arthritis (PsA) (subgroups)

Trend of higher mortality in patients exposed to biologic therapies, but not for PsA

Original publication

Risk of Mortality of People With Psoriasis and Psoriatic Arthritis in Taiwan: A Nationwide Cohort Study. J Rheumatol. Published 15 February 2025. doi:10.3899/jrheum.2024-1032

Composed by AI from the published abstract and checked against it. How Briefs are made →

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