Spondyloarthritis & psoriatic arthritis
Risk of cancer in Korean patients with psoriatic arthritis: a nationwide population-based cohort study
Main finding · Overall cancerResult — go to the resultAdjusted hazard ratio 1.20 95% CI 1.02–1.41Authors' conclusion
The risk of overall cancer was higher in patients with PsA than in the general population. Patients with PsA had increased risks of NMSC, lymphoma and thyroid cancer compared with the general population.
Study context
- Population
- Patients newly diagnosed with PsA and matched controls, nationwide population-based cohort in Korea, 2010 to June 20211:10 matched cohort
- Participants
- 4,688 vs 46,880
- Exposure
- PsA vs age- and sex-matched controls
- PsAn = 4,688
- Controlsn = 46,880reference
- Outcome
- Incidence of overall and specific cancers
Methodological details1:10 age-matched and sex-matched controls
- 1:10 age-matched and sex-matched controls
Main finding
Overall cancer
Adjusted hazard ratio
1.20
95% CI 1.02–1.41
Events by group
PsAvs Controls
aHR 1.20 (95% CI 1.02–1.41)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | aHR (95% CI) | |
|---|---|---|
| Overall cancer excluding NMSCSignificance disappeared when NMSC excluded | 1.16 (0.98–1.37) | |
| NMSC | 3.64 (1.61–8.23) | |
| Lymphoma | 2.63 (1.30–5.30) | |
| Thyroid cancer | 1.83 (1.18–2.85) | |
| 0.10.31310Adjusted hazard ratio (log scale) |
Original publication
Risk of cancer in Korean patients with psoriatic arthritis: a nationwide population-based cohort study. RMD Open. Published 23 March 2023. doi:10.
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