Lupus & antiphospholipid syndrome
Relationship of serum and dietary vitamin D with high cardiometabolic risk in Mexican systemic lupus erythematosus patients: A cross-sectional study
Authors' conclusion
A pattern of Calcidiol deficiency, inadequate vitamin D dietary intake, and non-adherence to a DP rich in vitamin D food sources was related to high cardiometabolic risk in SLE patients and HS.
Study context
- Population
- Mexican systemic lupus erythematosus (SLE) patients and healthy subjects
- Participants
- 224 vs 201
- Exposure
- Serum and dietary vitamin D vs cardiometabolic risk in SLE patients and healthy subjects
- SLEn = 224
- Healthy subjects (HS)n = 201reference
- Outcome
- Relationship of serum and dietary vitamin D with cardiometabolic risk
Main finding
As reported in the abstract
- Calcidiol deficiency (<20 ng/mL): higher risk of excess weight by body mass index (BMI) (≥25 kg/m²), p = .02
- 1.66-fold
- Calcidiol deficiency: higher risk of low high-density lipoprotein-cholesterol (HDL-C) (<40 mg/dL), p < .001
- 2.25-fold
- Calcidiol deficiency: higher risk of high triglycerides (TG) ≥150 mg/dL, p = .02
- 1.74-fold
- Inadequate vitamin D dietary intake: higher risk of non-healthy waist circumference (WC) (>80 cm), p < .01
- 1.92-fold
- Inadequate vitamin D dietary intake: higher risk of android WHR (≥85), p < .01
- 2.05-fold
- Inadequate vitamin D dietary intake: higher risk of excess weight, p = .02
- 1.72-fold
Observational data: associations, not effects.
Further findings
Non-adherence to a DP rich in vitamin D food sources
- In HS: higher risk of calcidiol deficiency
- 2.11-fold
- Associated with higher WC, WHR, triglycerides, and lower HDL-C
Original publication
Relationship of serum and dietary vitamin D with high cardiometabolic risk in Mexican systemic lupus erythematosus patients: A cross-sectional study. Lupus. Published 6 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →