Relationship Between Knee Biomechanics and Pain in People With Knee Osteoarthritis: A Systematic Review and Meta‐Analysis
Authors' conclusion
Some knee gait biomechanics were associated with pain in this cohort.
Study context
- Population
- People with medial/nonspecific knee OA; knee biomechanics during gait and pain40 studies
- Outcome
- Cross-sectional relationship between knee biomechanics during gait and pain
Methodological detailsrandom-effects meta-analyses, metaregression, Four online databases searched from inception to July 2021, Methodological quality ranged from 4 to 9/10
- Random-effects meta-analyses
- Metaregression
- Four online databases searched from inception to July 2021
- Methodological quality ranged from 4 to 9/10
Pooled result
As reported in the abstract
Correlation of knee gait biomechanics with pain
- Peak KAM pooled (early stance and overall), r
- 0.00 (95% CI −0.12, 0.11; k = 16)
- Early stance peak KAM, r
- −0.09 (95% CI −0.18, −0.002; k = 12)
- Overall peak KAM during stance, r
- 0.30 (95% CI 0.17, 0.42; k = 4)
- BMI moderated the peak KAM-pain relationship (metaregression), P
- P < 0.001
- KAM impulse, r
- 0.23 (95% CI 0.04, 0.40; k = 5)
- Varus thrust vs none, odds of reporting pain
- 3.84 (95% CI 1.72, 8.53; k = 3)
Further pooled results
Differences in knee biomechanics between symptomatic and asymptomatic participants
- Meta-analyses nonsignificant
Original publication
Relationship Between Knee Biomechanics and Pain in People With Knee Osteoarthritis: A Systematic Review and Meta‐Analysis. Arthritis Care Res (Hoboken). Published 28 December 2022. doi:10.
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