Relationship Between Gout Flare States and Patient‐Reported Outcomes After Allopurinol Initiation
Authors' conclusion
The majority of people were able to achieve gout flare PASS or LDA in the second six months after commencing allopurinol. As flare burden increases, so does the impact of gout on the patient.
Study context
- Population
- People with gout starting allopurinol in a 12-month RCT of low-dose colchicine vs placebo for the first 6 monthspost hoc analysis of RCT data
- Participants
- 68 / 34 / 77
- Comparison
- Gout flare states: Patient-acceptable symptom state (PASS) vs low disease activity (LDA) vs non-LDA/PASS
- PASSn = 68
- LDAn = 34
- non-LDA/PASSn = 77
- Primary endpoint
- Relationship between gout flare states and patient-reported outcomes (HAQ, EQ-5D-3L, gout-specific BIPQ)
- Follow-up
- Final six months of the study
Methodological detailspost hoc analyses of variance
- Post hoc analyses of variance
Primary result
As reported in the abstract
Gout flare state in the final six months
Original publication
Relationship Between Gout Flare States and Patient‐Reported Outcomes After Allopurinol Initiation. Arthritis Care Res (Hoboken). Published 23 January 2025. doi:10.
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