Recommendations for the management of hip and knee osteoarthritis: A systematic review of clinical practice guidelines
Authors' conclusion
Higher-quality guidelines for hip and knee osteoarthritis consistently recommend clinicians implement exercise, education, and weight management, alongside consideration of Non-Steroidal Anti-Inflammatory Drugs and intra-articular corticosteroid injections (knee).
Study context
- Population
- Clinical practice guidelines for hip and knee OA management7 higher-quality and 18 lesser-quality guidelines
- Participants
- 7 vs 18
- Comparison
- Higher-quality guidelines vs Lesser-quality guidelines
- Higher-quality guidelinesn = 7
- Lesser-quality guidelinesn = 18
- Outcome
- Guideline quality (AGREE II) and consistency in recommendations across higher-quality guidelines
Methodological detailsAGREE II quality appraisal, descriptive synthesis of consistency, prospectively registered, Eight databases, guideline repositories and professional associations websites searched on 27/10/2022
- AGREE II quality appraisal
- Descriptive synthesis of consistency
- Prospectively registered
- Eight databases, guideline repositories and professional associations websites searched on 27/10/2022
Pooled result
As reported in the abstract
Consistency of recommendations across higher-quality guidelines
- Consistently recommended in favour: education, exercise, weight management and NSAIDs (hip and knee), intra-articular corticosteroid injections (knee)
- Consistently recommended against: hyaluronic acid (hip) and stem cell (hip and knee) injections; arthroscopy
- Less consistent: other pharmacological recommendations (e.g., paracetamol, intra-articular corticosteroid (hip), hyaluronic acid (knee)) and adjunctive treatments (e.g., acupuncture)
- No higher-quality guidelines considered arthroplasty
Further pooled results
AGREE II domain scores, higher-quality guidelines
- Domain scores >60% except applicability
- > 60%
- Applicability, average
- 46%
Original publication
Recommendations for the management of hip and knee osteoarthritis: A systematic review of clinical practice guidelines. Osteoarthritis Cartilage. Published 30 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →