Appraisal of quality and analysis of the similarities and differences between osteoarthritis Clinical Practice Guideline recommendations: A systematic review
Authors' conclusion
There were associations between guideline quality and agreement scores.
Study context
- Population
- Clinical Practice Guidelines (CPGs) for managing hip and knee osteoarthritis (OA) in adults ≥18 yearsCPGs, 8 countries, 4 international organisations
- Participants
- 25 cpgs
- Outcome
- Contextual and methodological factors contributing to conflicting recommendations for hip and knee OA; guideline quality (AGREE-II/AGREE-REX) and heterogeneity of recommendations (Weighted Fleiss Kappa)
Methodological detailsAGREE-II and AGREE-REX quality appraisal, Weighted Fleiss Kappa
- AGREE-II and AGREE-REX quality appraisal
- Weighted Fleiss Kappa
Pooled result
As reported in the abstract
- Highest overall AGREE-II quality: ACR, EULAR, NICE, OARSI and RACGP
- 83%
- Highest overall AGREE-REX: BMJ Arthroscopy
- 80%
- Highest overall AGREE-REX: RACGP
- 78%
- Highest overall AGREE-REX: NICE
- 76%
- Least agreement, pharmacological recommendations (K): ESCEO and NICE
- −0.14
- Least agreement, pharmacological recommendations (K): ACR
- −0.08
- Least agreement, pharmacological recommendations (K): RACGP
- −0.01
- Highest agreement (K): RACGP and NICE
- 0.53
- Highest agreement (K): RACGP and ACR
- 0.61
- Highest agreement (K): NICE and ACR
- 0.91
Original publication
Appraisal of quality and analysis of the similarities and differences between osteoarthritis Clinical Practice Guideline recommendations: A systematic review. Osteoarthritis Cartilage. Published 5 March 2024. doi:10.
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