Real-world care patterns and specialist encounters of patients with systemic autoimmune rheumatic disease-related interstitial lung disease in the United States: a retrospective administrative claims database analysis
An erratum to this article was published (Rheumatology (Oxford), 5 May 2026 ↗)
Authors' conclusion
The study highlights the complex diagnostic journey of patients with SARD-ILD.
Study context
- Population
- Adults with SARD-ILD, ≥36 months continuous enrolment before index interstitial lung disease (ILD) diagnosis, US Healthcare Integrated Research Database (2006–2023)
- Participants
- 2,526 adults
- Exposure
- Pulmonologist visit within 90 days of respiratory symptom onset vs no such visit (subset with prior respiratory symptoms)
- Outcome
- Demographics, clinical characteristics and care patterns before ILD diagnosis
- Follow-up
- Before ILD diagnosis
Methodological detailsadministrative claims database, descriptive analysis, Cox proportional hazards model
- Administrative claims database
- Descriptive analysis
- Cox proportional hazards model
Main finding
As reported in the abstract
Characteristics and care before ILD diagnosis
- Mean age (years)
- 62.6
- Female
- 75.4%
- ≥1 all-cause hospitalization
- 61.8%
- Chest CT
- 80.1%
- High-resolution CT
- 59.0%
- Pulmonary function tests
- 60.3%
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| ILD diagnosis from respiratory symptom onset (subgroup with prior respiratory symptoms)18% more likely to be diagnosed with ILD | 1.18 (1.03–1.35) | P = 0.017 | |
| 0.512Hazard ratio (log scale) |
Original publication
Real-world care patterns and specialist encounters of patients with systemic autoimmune rheumatic disease-related interstitial lung disease in the United States: a retrospective administrative claims database analysis. Rheumatology (Oxford). Published 23 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →