Spondyloarthritis & psoriatic arthritis
Racial and ethnic determinants of psoriatic arthritis phenotypes and disease activity
Authors' conclusion
Despite similar swollen joint counts and medication use, non-white individuals have higher tender joint counts compared with White individuals. Phenotypically, they also were more likely to have radiographic axial involvement.
Study context
- Population
- Consecutive patients with PsA from a large, diverse metropolitan area
- Participants
- 817 patients
- Exposure
- Hispanic and non-white vs non-Hispanic White individuals with PsA
- Outcome
- Disease characteristics by race and ethnicity
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
- Population: 77.4% non-Hispanic White, 2.2% Black, 7.1% Asian, 9.9% other races or multiracial; 11.8% Hispanic
- Hispanic and non-white individuals also had high rates of radiographic axial disease
- Hispanic and non-white vs Non-Hispanic White: P = 0.033
- Hispanic and non-white vs Non-Hispanic White: P = 0.308
- Hispanic and non-white vs Non-Hispanic White: P = 0.171
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Hispanic vs non-Hispanic White: tender joint counts, RAPID3 scores, moderate-severe psoriasisHispanic vs Non-Hispanic White · higher tender joint counts | P = 0.029 |
| Hispanic vs non-Hispanic White: tender joint counts, RAPID3 scores, moderate-severe psoriasisHispanic vs Non-Hispanic White · higher RAPID3 scores | P = 0.004 |
| Hispanic vs non-Hispanic White: tender joint counts, RAPID3 scores, moderate-severe psoriasisHispanic vs Non-Hispanic White · more likely moderate-severe psoriasis | P = 0.010 |
Original publication
Racial and ethnic determinants of psoriatic arthritis phenotypes and disease activity. Rheumatology (Oxford). Published 1 February 2024. doi:10. 1093/ rheumatology/ keae066
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