Spondyloarthritis & psoriatic arthritis
Comparison of the ASAS Health Index in patients classified as radiographic axial spondyloarthritis (axSpA) or non-radiographic axSpA in the ASAS Health Index international validation study
Authors' conclusion
Overall health and functioning are similarly affected in patients with r-axSpA and nr-axSpA. Female patients, having worse physical function, disease activity, anxiety and depressive symptoms were independently associated with higher ASAS HI scores.
Study context
- Population
- Patients ≥18 years diagnosed with axSpA, 23 countries
- Participants
- 976 patients
- Exposure
- Radiographic axial spondyloarthritis (r-axSpA) vs nr-axSpA
- r-axSpAn = 703
- nr-axSpAn = 273reference
- Outcome
- ASAS HI scores (higher = worse)
Methodological detailsancillary analysis of the ASAS HI international validation project, 23 countries, univariable and multivariable analysis
- Ancillary analysis of the ASAS HI international validation project
- 23 countries
- Univariable and multivariable analysis
Main finding
ASAS HI score
β
−0.19
95% CI −0.56 to 0.19
By group
r-axSpA
6.8
spread as printed 4.4
nr-axSpA
6.0
spread as printed 4.0
As reported in the abstract
Observational data: associations, not effects.
Further findings
Factors associated with higher ASAS HI scores (multivariable)
- Female gender, worse physical function (BASFI), disease activity (ASDAS) and anxiety and depressive symptoms (HADS) associated with higher ASAS HI scores
- No interactions between axSpA phenotype and significant variables
Original publication
Comparison of the ASAS Health Index in patients classified as radiographic axial spondyloarthritis (axSpA) or non-radiographic axSpA in the ASAS Health Index international validation study. RMD Open. Published 31 January 2024. doi:10.
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