Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States
Authors' conclusion
In this national sample of hospitalized pediatric patients with AAV, Hispanic race or ethnicity was a statistically significant predictor of severe AAV disease and ESRD, and household income was inversely associated with renal transplantation among those with ESRD.
Study context
- Population
- Pediatric AAV hospitalizations in the United States, 2016 and 2019 Kids' Inpatient Database
- Participants
- 673 unweighted hospitalizations
- Exposure
- Race and ethnicity and household income quartile, associations with severe AAV, end-stage renal disease (ESRD) and renal transplantation
- Outcome
- Severe AAV disease (ICD codes indicating organ failure, complications or life-sustaining procedures), ESRD, and renal transplantation among those with ESRD
Methodological detailsnational database (2016 and 2019 Kids' Inpatient Database), univariate and multivariable logistic regression
- National database (2016 and 2019 Kids' Inpatient Database)
- Univariate and multivariable logistic regression
Main finding
As reported in the abstract
Each group vs highest quartileAdjusted odds ratio (95% CI)
Hispanicsevere disease
1.61(1.01–2.56)
HispanicESRD
1.98(1.04–3.77)
Lowest-income quartilerenal transplantation among patients with ESRD
0.18(0.04–0.71)
- Hospitalizations with at least one severe disease feature
- 59%
Observational data: associations, not effects.
Original publication
Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States. Arthritis Care Res (Hoboken). Published 18 May 2026. doi:10. 1002/ acr. 80088
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