Race, ethnicity and patient-reported outcomes in childhood-onset systemic lupus erythematosus
Authors' conclusion
In this multiethnic paediatric lupus cohort, PROMIS global health was lower when compared with the general paediatric US population. Moreover, PROMIS global health, pain interference, and physical function mobility did not vary across races/ethnicities.
Study context
- Population
- Childhood-onset SLE patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry within two years of diagnosis, meeting ACR and/or SLICC criteria83.8% female
- Participants
- 425 patients
- Exposure
- Race/ethnicity groups
- Outcome
- Association of race/ethnicity with PROMIS scores
- Follow-up
- Registry enrolment
Methodological detailsregistry-based, multivariable linear regression
- Registry-based
- Multivariable linear regression
Main finding
As reported in the abstract
Association of race/ethnicity with PROMIS scores (multivariable linear regression)
- No association between race/ethnicity and PROMIS scores
Observational data: associations, not effects.
Further findings
Overall PROMIS Global Health T-score · baseline
- Mean T-score (SD 6.5), >1 SD below general population mean of 50
- 38.6
Original publication
Race, ethnicity and patient-reported outcomes in childhood-onset systemic lupus erythematosus. Clin Exp Rheumatol. Published 10 May 2022. doi:10.
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