Pulmonary hypertension in juvenile-onset systemic lupus erythematosus: a case series
Authors' conclusion
JSLE has a high associated cardiovascular morbidity and mortality and early identification of treatable complications such as PHTN is vital.
Study context
- Population
- Children with juvenile-onset systemic lupus erythematosus (SLE) (JSLE) in the UK JSLE Cohort Study, 2006–2020; Pulmonary hypertension (PHTN) cases: four female children aged 4 to 15 years at JSLE presentation and 8 to 27 years at PHTN diagnosis4 PHTN cases
- Participants
- 665 children
- Outcome
- PHTN in JSLE
Methodological detailsUK JSLE Cohort Study
- UK JSLE Cohort Study
Main finding
As reported in the abstract
Children with JSLE identified as having PHTN
four (0.6%)
PHTN cases presenting with cardiovascular symptoms and/or signs
3 of 4
PHTN cases treated with Rituximab, with a good long-term outcome
3 of 4
Observational data: associations, not effects.
Original publication
Pulmonary hypertension in juvenile-onset systemic lupus erythematosus: a case series. Clin Exp Rheumatol. Published 30 September 2022. doi:10.
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