Fibromyalgia & musculoskeletal pain

Prevalence of non-coeliac gluten sensitivity and assessment of the response to gluten-free diet in a cohort of patients with fibromyalgia

Rheumatology (Oxford)Published Uncontrolled prospective experimental study

Authors' conclusion

A NCGS prevalence similar to that estimated in the general population was found.

Study context

Population
Patients with FM from a specialised hospital unit
Participants
142 patients
Outcome
Prevalence of non-coeliac gluten sensitivity (Salerno Experts' Criteria)
Methodological detailssingle specialised hospital unit
  • Single specialised hospital unit

Main finding

As reported in the abstract

NCGS prevalence

Non-coeliac gluten sensitivity (NCGS) prevalence

5.6%

Observational data: associations, not effects.

Further findings

Response to 6-week gluten-free diet (improvement in intestinal symptoms) · six weeks

Responded to gluten-free diet (GFD)
21.8%
Responders not fulfilling Salerno Experts' Criteria
74.2%

Predictors of GFD response

Diarrhoea, intraepithelial lymphocytosis and lower anxiety were predictive of GFD response
No predictive factors of NCGS criteria fulfilment found (low number of discriminators between gluten and placebo)

Original publication

Prevalence of non-coeliac gluten sensitivity and assessment of the response to gluten-free diet in a cohort of patients with fibromyalgia. Rheumatology (Oxford). Published 28 July 2022. doi:10.1093/rheumatology/keac434

Composed by AI from the published abstract and checked against it. How Briefs are made →

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