Fibromyalgia & musculoskeletal pain

Mediterranean diet and its low-antigenic and anti-inflammatory properties on fibromyalgia: a systematic review

Clin Exp RheumatolPublished Systematic review

Authors' conclusion

The articles studied within this review show that there is a relationship between the gut and how FM symptoms can be affected.

Study context

Population
Patients with fibromyalgia (FM); interventional and observational studies of the Mediterranean diet5 interventional, 5 observational studies
Outcome
FM-related symptoms with Mediterranean diet adherence
Methodological detailsPRISMA 2020, PubMed and Google Scholar searched, articles published 2019–2024, Sample sizes 13–84 in interventional and 84–442 in observational studies
  • PRISMA 2020
  • PubMed and Google Scholar searched
  • Articles published 2019–2024
  • Sample sizes 13–84 in interventional and 84–442 in observational studies

Pooled result

As reported in the abstract

  • Adherence to a Mediterranean diet associated with significant improvements in FM-related symptoms, incl. chronic widespread pain, autonomic dysfunction, persistent fatigue, sleep disturbances and cognitive impairments ('fibro fog')

Original publication

Mediterranean diet and its low-antigenic and anti-inflammatory properties on fibromyalgia: a systematic review. Clin Exp Rheumatol. Published 26 June 2025. doi:10.55563/clinexprheumatol/2usk4p

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