Lupus & antiphospholipid syndrome
Prevalence of frailty and prefrailty in systemic lupus erythematosus: A systematic review and meta-analysis
Authors' conclusion
Both frailty and prefrailty are highly prevalent conditions among patients with SLE.
Study context
- Population
- Patients with systemic lupus erythematosus (SLE); PubMed, Cochrane, EMBASE and Web of Science searched from inception to November 2024
- Participants
- 46,060 patients15 studies
- Outcome
- Prevalence of frailty and prefrailty in SLE
Methodological detailsquality assessment by Newcastle-Ottawa scale
- Quality assessment by Newcastle-Ottawa scale
Pooled result
As reported in the abstract
Pooled prevalence of frailty
27 %
95 % CI: 19 % - 36 %
Pooled prevalence of prefrailty
65 %
95 % CI: 54 % - 76 %
Further pooled results
Prevalence of frailty by measurement tool (subgroups)
%
- Frailty measured by Systemic Lupus International Collaborating Clinics-Frailty Index (SLICC-FI)
- 26 (95 % CI: 14 % to 41 %)
- Frailty assessed using Fried phenotype
- 22 (95 % CI: 18 % to 26 %)
Original publication
Prevalence of frailty and prefrailty in systemic lupus erythematosus: A systematic review and meta-analysis. Semin Arthritis Rheum. Published 6 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →