Spondyloarthritis & psoriatic arthritis

Prevalence and Predictors of Achieving Sustained Remission in Psoriatic Arthritis: A Swedish Nationwide Registry Study

J RheumatolPublished Retrospective cohort study

Authors' conclusion

A considerable proportion of patients with PsA receiving various b/tsDMARDs never achieved remission, and approximately half never achieved SR in this Swedish nationwide registry study.

Study context

Population
Patients with PsA initiating b/tsDMARDs registered in the Swedish Rheumatology Quality Register (SRQ), April 1999 to December 2019
Participants
4,669 patients48,773 visits
Outcome
Sustained remission (SR): DAS28-CRP ≤ 2.6, DAPSA28 ≤ 4 or PGA = 0 persisting during ≥ 2 consecutive visits for ≥ 6 months
Methodological detailsnationwide registry, logistic regression
  • Nationwide registry
  • Logistic regression

Main finding

As reported in the abstract

DAS28-CRP remission ever
81%
DAS28-CRP sustained remission (SR) at least once
54%
DAPSA28 remission ever
46%
DAPSA28 SR
24%
PGA remission ever
69%
PGA SR
38%

Observational data: associations, not effects.

Further findings

Male sex a positive predictor of SR by DAPSA28 and PGA but not by DAS28-CRP
Fewer swollen joints at baseline predicted SR according to all 3 remission criteria

Original publication

Prevalence and Predictors of Achieving Sustained Remission in Psoriatic Arthritis: A Swedish Nationwide Registry Study. J Rheumatol. Published 15 May 2025. doi:10.3899/jrheum.2024-1250

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