Sjögren's disease & overlap diseases
Prevalence and comorbidities of Sjogren's syndrome patients in the Community of Madrid: A population-based cross-sectional study
Authors' conclusion
The prevalence of SS in the Community of Madrid was similar to the overall prevalence worldwide observed in previous studies. SS was more frequent in women in their sixth decade. Two out of every three SS cases were pSS, while one-third were associated predominantly with rheumatoid arthritis and systemic lupus erythematosus.
Study context
- Population
- Sjogren's syndrome (SS) patients aged ≥18 years from the rare diseases information system (SIERMA), Community of Madrid, June 2015, confirmed by a physician92.8% female
- Participants
- 4,778 patients
- Exposure
- pSS vs sSS
- pSSn = 3,116
- sSSn = 1,662
- Outcome
- Prevalence of SS per 10,000 inhabitants aged ≥18 years
- Follow-up
- June 2015
Methodological detailspopulation-based
- Population-based
Main finding
As reported in the abstract
Prevalence of SS among people aged ≥18 years
pSS
5.5/10,000
95% CI 5.3–5.7
sSS
2.8/10,000
95% CI 2.7–2.9
- Prevalence of SS (overall), 95% CI 8.2-8.7
- 8.4/10,000
Observational data: associations, not effects.
Further findings
Age at study
- Mean age, years (SD 15.4)
- 64.3
Most prevalent associated autoimmune diseases in sSS
- RA
- 20.3%
- SLE
- 8.5%
Most common comorbidities
- Hypertension
- 40.8%
- Lipid disorders
- 32.7%
- OA
- 27.7%
- Depression
- 21.1%
Most prescribed medications
- NSAIDs
- 31.9%
- Topical ophthalmic therapies
- 31.2%
- Corticosteroids
- 28.0%
Original publication
Prevalence and comorbidities of Sjogren's syndrome patients in the Community of Madrid: A population-based cross-sectional study. Joint Bone Spine. Published 15 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →