Vasculitis & polymyalgia rheumatica
Prevalence and Clinical Characteristics of Vasculitis in the Alaska Native and American Indian Peoples of Alaska
Authors' conclusion
The prevalence of AAV (especially GPA) in AN/AI peoples is high. GCA prevalence is lower than White populations, but higher than many other populations.
Study context
- Population
- Adult Alaska Native and American Indian (AN/AI) peoples within the Alaska Tribal Health System (ATHS); denominator 2019 ATHS user population ≥ 18 (≥ 50 for GCA)
- Outcome
- Prevalence and clinical characteristics of vasculitis
Methodological detailselectronic health record query, medical record abstraction, age-adjusted prevalence
- Electronic health record query
- Medical record abstraction
- Age-adjusted prevalence
Main finding
As reported in the abstract
Age-adjusted prevalence
- All vasculitis, per 1,000,000 AN/AI adults
- 752 (95% CI 581-959)
- Systemic vasculitis (most common), per 1,000,000 adults
- 518 (95% CI 379-695)
- Antibody-associated vasculitis (AAV), per million adults
- 340 (95% CI 230-488)
- GCA, per 100,000 ≥ 50
- 28 (95% CI 12-56)
- Granulomatosis with polyangiitis (GPA) (most prevalent AAV subtype), per million adults
- 244 (95% CI 148-380)
Observational data: associations, not effects.
Further findings
Age at diagnosis
- AAV, mean age in years (SD 17); often high markers of inflammation and renal involvement
- 54.2
- GCA, mean age in years (SD 9.2)
- 69.6
Original publication
Prevalence and Clinical Characteristics of Vasculitis in the Alaska Native and American Indian Peoples of Alaska. Arthritis Care Res (Hoboken). Published 5 March 2025. doi:10. 1002/ acr. 25506
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