Spondyloarthritis & psoriatic arthritis
Prevalence and Associated Factors of Facet Joint Ankylosis in Patients With Axial Spondyloarthritis
Authors' conclusion
The prevalence of ankylosed facet joints is high in axSpA, especially in the thoracic segment. The whole spine ankylosed facet joint score is significantly associated with a history of uveitis, ASDAS, sacroiliitis, and syndesmophyte score.
Study context
- Population
- Patients with axial spondyloarthritis (axSpA) undergoing whole spine low-dose CT
- Participants
- 161 patients
- Exposure
- Reader 1 vs Reader 2
- Outcome
- Prevalence of facet joint ankylosis (right and left, C2-S1; score 0 to 46) in the whole spine
Methodological detailswhole spine low-dose CT, 2 readers, generalized linear model with negative binomial distribution
- Whole spine low-dose CT
- 2 readers
- Generalized linear model with negative binomial distribution
Main finding
As reported in the abstract
≥ 1 ankylosed facet joint
Observational data: associations, not effects.
Further findings
Mean
| Outcome | Reader 1 | Reader 2 |
|---|---|---|
| Whole spine facet joint ankylosis score | 6.6 (SD 11.2) | 4.2 (SD 8.4) |
Factors associated with whole spine facet joint ankylosis score
- Score positively correlated with Ankylosing Spondylitis Disease Activity Score (ASDAS) and CT Syndesmophyte Score (CTSS)
- Multivariable: associated with ASDAS, sacroiliitis, CTSS and history of uveitis in both readers
Factors associated with whole spine facet joint ankylosis score (radiographic axSpA subgroup)
- Uveitis history, ASDAS and CTSS associated with score
Original publication
Prevalence and Associated Factors of Facet Joint Ankylosis in Patients With Axial Spondyloarthritis. J Rheumatol. Published 15 January 2023. doi:10.
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