Autoinflammatory & rare systemic diseases
Pregnancy outcomes in patients with familial Mediterranean fever: systematic review and meta-analysis
Pooled result · Preterm deliveryResult — go to the resultOdds ratio 1.67 95% CI 1.05–2.67Authors' conclusion
FMF was significantly associated with preterm delivery and insignificantly associated with fetal growth restriction and hypertensive disorders.
Study context
- Population
- Pregnancies in patients with familial Mediterranean fever vs healthy controls; case-control, cohort and randomised studies9 studies, pregnancies
- Participants
- 177,735 pregnancies
- Comparison
- FMF vs healthy controls
- FMFn = 1,242
- Healthy controlsn = 176,493reference
- Outcome
- Preterm delivery
Methodological detailsrandom-effects model, All included studies were observational
- Random-effects model
- All included studies were observational
Pooled result
As reported in the abstract
Odds ratio
1.67
95% CI 1.05–2.67
FMFvs Healthy controls
OR 1.67 (95% CI 1.05–2.67)
Further pooled results
| Outcome | OR (95% CI) | |
|---|---|---|
| Fetal growth restrictionI2 = 0% | 1.45 (0.90–2.34) | |
| Hypertensive disorders during pregnancyI2 = 0% | 1.28 (0.87–1.87) | |
| 0.512Odds ratio (log scale) |
Original publication
Pregnancy outcomes in patients with familial Mediterranean fever: systematic review and meta-analysis. Rheumatology (Oxford). Published 18 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →