Preferences for preventive treatments for rheumatoid arthritis: discrete choice survey in the UK, Germany and Romania
Authors' conclusion
Effective preventive pharmacological treatments for RA were acceptable to most participants. The relative importance of treatment attributes and likely uptake of fixed treatment profiles were predicted by participant characteristics.
Study context
- Population
- Adults recruited via survey panels in the UK, Germany and Romania, asked to assume arthralgia with a 60% chance of developing rheumatoid arthritis (RA) in the next 2 yearscompleted surveys analysed
- Participants
- 2,959 adults
- Exposure
- Hypothetical preventive treatments vs no treatment
- Outcome
- Preferences for preventive therapies for RA (relative importance of attributes, benefit-risk trade-offs, predicted uptake)
Methodological detailsweb-based survey, discrete choice experiment, latent class models
- Web-based survey
- Discrete choice experiment
- Latent class models
Main finding
As reported in the abstract
Maximum acceptable risk for a 40% reduction in the chance of getting RA (60% to 20%)
Mild side effects
21.7%
Serious infection
19.1%
Serious side effects
2.2%
Observational data: associations, not effects.
Original publication
Preferences for preventive treatments for rheumatoid arthritis: discrete choice survey in the UK, Germany and Romania. Rheumatology (Oxford). Published 7 September 2022. doi:10.
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