Associations of Socioeconomic Status With Disease Progression in African Americans With Early Rheumatoid Arthritis
Authors' conclusion
Low educational attainment and nonprofessional occupation status were associated with increased worsening of patient-reported outcomes. However, there were no corresponding increases in radiographically assessed erosion or JSN score progression.
Study context
- Population
- African American patients with early rheumatoid arthritis (RA) (<2 years duration)101 radiographs
- Exposure
- Low vs higher socioeconomic status (SES) measures
- Outcome
- Disease progression: change in radiographs (total erosion and JSN scores, hands and feet) and patient-reported outcomes (pain, fatigue, disability, learned helplessness)
- Follow-up
- 60 months
Methodological detailslogistic regression with mixed effects accounting for study site
- Logistic regression with mixed effects accounting for study site
Main finding
As reported in the abstract
Worsening pain
Adjusted odds ratio (95% CI)
Low education
5.86(3.05–11.3)
Low occupation status
2.55(1.54–4.21)
Observational data: associations, not effects.
Further findings
Worsened learned helplessness · 60 months
| OR (95% CI) | ||
|---|---|---|
| Without high-school diploma | 1.92 (1.37–2.67) | |
| 0.20.5125Odds ratio (log scale) |
Increased disability scores · 60 months
| OR (95% CI) | ||
|---|---|---|
| Block group poverty ≥20% | 1.95 (1.17–3.25) | |
| 0.20.5125Odds ratio (log scale) |
Erosion or JSN score progression · 60 months
- No association between SES measures and erosion or JSN score progression
Original publication
Associations of Socioeconomic Status With Disease Progression in African Americans With Early Rheumatoid Arthritis. Arthritis Care Res (Hoboken). Published 6 September 2022. doi:10.
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