Preferences for COVID-19 Vaccination in People With Chronic Immune-Mediated Inflammatory Diseases
Authors' conclusion
Patients perceived the benefits of COVID-19 vaccination to outweigh rare serious risks and disease flare.
Study context
- Population
- People with chronic immune-mediated inflammatory diseases (IMIDs) recruited May–August 2021 through patient groups and clinics in Canada (IBD 48%, RA 38%, SLE 16%)89% female, mean age 46 yrs
- Participants
- 551 people
- Outcome
- Relative importance (RI) of attributes relevant to COVID-19 vaccination
Methodological detailsonline survey, latent class analysis
- Online survey
- Latent class analysis
Main finding
As reported in the abstract
Relative importance of vaccine attributes
Vaccine effectiveness (most important)
66%
Disease flare
21%
Rare but serious risks
9%
Number/timing of injections
4%
Observational data: associations, not effects.
Further findings
Maximum acceptable risk of disease flare requiring treatment change for a 10% absolute increase in effectiveness
- Acceptable flare risk
- ≤ 8.8%
Preference heterogeneity (3 latent classes)
- Class with greatest aversion to disease flare more likely male and lower income, but still valued effectiveness higher than other attributes
Original publication
Preferences for COVID-19 Vaccination in People With Chronic Immune-Mediated Inflammatory Diseases. J Rheumatol. Published 15 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →