Vasculitis & polymyalgia rheumatica

Prediction model for respiratory-related mortality in microscopic polyangiitis with interstitial lung disease: multicentre REVEAL cohort study

Rheumatology (Oxford)Published Prognostic model development study

Authors' conclusion

Our study indicates that the MPF model may help predict respiratory-related death in patients with MPA with ILD.

Study context

Population
Japanese patients with microscopic polyangiitis (MPA) with interstitial lung disease (ILD), REVEAL cohort, May 2005–June 2021median follow-up 3.8 years
Participants
115 patients
Outcome
Respiratory-related mortality
Methodological detailsmulticentre cohort study, REVEAL cohort, univariate and multivariate analysis adjusted for age and treatment
  • Multicentre cohort study
  • REVEAL cohort
  • Univariate and multivariate analysis adjusted for age and treatment

Performance

As reported in the abstract

median follow-up of 3.8 years

Died of respiratory-related diseases

26

Due to respiratory infection

18

69%

Diffuse alveolar haemorrhage

3

12%

Exacerbation of ILD

5

19%

Original publication

Prediction model for respiratory-related mortality in microscopic polyangiitis with interstitial lung disease: multicentre REVEAL cohort study. Rheumatology (Oxford). Published 26 August 2023. doi:10.1093/rheumatology/kead444

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