Post-traumatic stress disorder and post-traumatic stress symptoms in patients with systemic autoimmune diseases during the COVID-19 pandemic
Authors' conclusion
Patients with SAD, and, in particular, patients with connective tissue diseases reported an increased risk of developing stress-related psychopathological symptoms
Study context
- Population
- Patients with systemic autoimmune disease (SAD) during the COVID-19 pandemic, Rheumatology and Psychiatric Clinics, Azienda Ospedaliero Universitaria Pisana (AOUP), Pisa, Italy (PERMAS project)
- Participants
- 252 patients
- Exposure
- Connective tissue disease vs arthritis vs systemic vasculitis
- Connective tissue diseasen = 131
- Arthritisn = 101
- Systemic vasculitisn = 20
- Outcome
- PTSD and post-traumatic stress symptoms (TALS-SR and Impact of Event Scale-Revised (IES-R))
Main finding
As reported in the abstract
Prevalence of full-blown and partial PTSD across diagnostic groups
- Diagnostic groups differed significantly in prevalence of full-blown and partial post-traumatic stress disorder (PTSD)
- p=0.001
Observational data: associations, not effects.
Further findings
Factors associated with Trauma and Loss Spectrum-Self Report (TALS-SR) scores
- Connective tissue disease and SF-36 significantly associated with TALS-SR scores, univariate analysis
- P < 0.001
- Connective tissue disease and SF-36 significantly associated with TALS-SR scores, multivariate analysis
- P < 0.025; p<0.001
Age and gender across diagnostic groups
- Groups differed significantly in age
- P < 0.001
- Groups differed significantly in gender
- P < 0.001
Original publication
Post-traumatic stress disorder and post-traumatic stress symptoms in patients with systemic autoimmune diseases during the COVID-19 pandemic. Clin Exp Rheumatol. Published 24 October 2023. doi:10.
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