Systemic sclerosis & Raynaud's

Performance of the EULAR Systemic sclerosis Impact of Disease (ScleroID) questionnaire as a patient-reported outcome measure for patients with diffuse systemic sclerosis

RMD OpenPublished Validation study

Authors' conclusion

The European Alliance of Associations for Rheumatology (EULAR) ScleroID performs well for patients with dcSSc.

Study context

Population
Patients with diffuse cutaneous SSc (dcSSc) from the large, multicentric ScleroID cohort (29% male, median age 54 years)analysed
Participants
152 patients
Outcome
Performance of ScleroID in dcSSc according to the OMERACT filter
Methodological detailscohort, multicentre, longitudinal arm with reliability visit at 7±3 days and 12-month follow-up, OMERACT filter
  • Cohort
  • Multicentre
  • Longitudinal arm with reliability visit at 7±3 days and 12-month follow-up
  • OMERACT filter

Performance

As reported in the abstract

Construct validity, internal consistency, reliability and sensitivity to change of ScleroID
Test or modelSpearman's correlation with SSc-HAQ (95% CI 0.69, 0.86)Spearman's correlation with HAQ-DI (95% CI 0.60, 0.80)Spearman's correlation with SF-36 physical score (95% CI −0.77, −0.60)Cronbach's alphaSplit-half reliability coefficientTest-retest ICC (95% CI 0.84, 0.92)Standardised response mean, improved subgroupStandardised response mean, worsened subgroup
dcSSc0.790.72−0.690.870.880.89−0.630.48

dcSSc

Spearman's correlation with SSc-HAQ (95% CI 0.69, 0.86)0.79
Spearman's correlation with HAQ-DI (95% CI 0.60, 0.80)0.72
Spearman's correlation with SF-36 physical score (95% CI −0.77, −0.60)−0.69
Cronbach's alpha0.87
Split-half reliability coefficient0.88
Test-retest ICC (95% CI 0.84, 0.92)0.89
Standardised response mean, improved subgroup−0.63
Standardised response mean, worsened subgroup0.48

Original publication

Performance of the EULAR Systemic sclerosis Impact of Disease (ScleroID) questionnaire as a patient-reported outcome measure for patients with diffuse systemic sclerosis. RMD Open. Published 27 November 2024. doi:10.1136/rmdopen-2024-004653

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