Systemic sclerosis & Raynaud's
Peer‐Led Symptom Management Intervention to Enhance Resilience in People With Systemic Sclerosis: Mediation Analysis From a Randomized Clinical Trial
Authors' conclusion
For participants in the intervention who had positive improvements in their physical and psychological symptoms, increased resilience was a mechanism for these improvements.
Study context
- Population
- People with systemic sclerosis (SSc)
- Participants
- 173 people
- Comparison
- 12-week online peer-led symptom management intervention vs waitlist control
- Primary endpoint
- Mediation by change in resilience (Connor-Davidson Resilience Scale) of intervention effects on changes in fatigue, pain interference and depressive symptoms
- Follow-up
- Week 12
Methodological detailscausal mediation analysis, linear mixed effect regression
- Causal mediation analysis
- Linear mixed effect regression
Primary result
As reported in the abstract
Indirect (mediated by resilience) effects of the intervention
Indirect effect on fatigue
−1.41
95% CI −2.41 to −0.41
Intervention
Indirect effect on pain interference
−0.86
95% CI −1.65 to −0.08
Intervention
Indirect effect on depressive symptoms
−1.99
95% CI −3.16 to −0.81
Intervention
Further findings
- Intervention participants reported improvements in resilience
- P < 0.001
Original publication
Peer‐Led Symptom Management Intervention to Enhance Resilience in People With Systemic Sclerosis: Mediation Analysis From a Randomized Clinical Trial. Arthritis Care Res (Hoboken). Published 31 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →