Patterns of clinical joint inflammation in juvenile idiopathic arthritis
Primary result · Joint inflammation during follow-up in the same jointResult — go to the resultOdds ratio 3.9 95% CI 3.5–4.4Authors' conclusion
In JIA, joint inflammation has the tendency to recur multiple times in joints that are clinically inflamed at disease onset.
Study context
- Population
- Children with recent-onset oligoarticular, RF-negative polyarticular and psoriatic juvenile idiopathic arthritis (JIA) in the BeSt for Kids study, clinically assessed during 2 years (10 study visits)joints of 91 patients
- Participants
- 6,097 children
- Comparison
- Joints clinically inflamed at baseline vs joints not inflamed at baseline
- Inflamed at baselinen = 897
- Primary endpoint
- Joint inflammation during follow-up in the same joint
- Follow-up
- 2 years
Methodological detailsjoint-level analysis, multilevel mixed-effects logistic regression, Poisson model
- Joint-level analysis
- Multilevel mixed-effects logistic regression
- Poisson model
Primary result
As reported in the abstract
Odds ratio
3.9
95% CI 3.5–4.4
Events by treatment group
Inflamed at baseline
42%
377 of 897
Inflamed at baselinevs Not inflamed at baseline
OR 3.9 (95% CI 3.5–4.4)
Further findings
| Outcome | IRR (95% CI) | |
|---|---|---|
| Number of episodes of recurrent joint inflammation | 1.6 (1.2–2.1) | |
| 0.512Incidence rate ratio (log scale) |
Joints clinically inflamed at baseline
- Joints clinically inflamed at baseline (897 of 6097)
- 15%
Original publication
Patterns of clinical joint inflammation in juvenile idiopathic arthritis. RMD Open. Published 16 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →