Fibromyalgia & musculoskeletal pain

Patient-Reported Impact of Symptoms in Fibromyalgia (PRISM-FM)

J RheumatolPublished Cross-sectional study

An erratum to this article was published (J Rheumatol, 1 Jul 2024 ↗)

Authors' conclusion

Participants with FM identify a variety of symptoms that significantly affect their daily lives. Many of these symptoms, such as fatigue, sleep disturbance, and activity limitation, are life-altering and not related to traditional diagnostic criteria. Symptom prevalence in this population varies across subgroups based on demographic categories and disability status.

Study context

Population
Adults with fibromyalgia (FM)plus 15 interviewed
Participants
1,085 adults
Outcome
Prevalence and relative importance (scale 0-4) of 149 symptoms representing 14 symptomatic themes
Methodological detailsinternational, semistructured interviews (qualitative phase), subgroup analysis
  • International
  • Semistructured interviews (qualitative phase)
  • Subgroup analysis

Main finding

As reported in the abstract

Prevalence: pain
99.8%
Prevalence: muscle tenderness
99.8%
Prevalence: fatigue
99.3%
Effect on life: fatigue
2.88
Effect on life: pain
2.85
Effect on life: muscle tenderness
2.79
Effect on life: impaired sleep and daytime sleepiness
2.70

Observational data: associations, not effects.

Further findings

Factors associated with symptomatic theme prevalence (subgroups)

Most strongly associated with modified Rankin Scale level of disability, disability status, and change in employment status (on disability vs not on disability)

Original publication

Patient-Reported Impact of Symptoms in Fibromyalgia (PRISM-FM). J Rheumatol. Published 15 January 2024. doi:10.3899/jrheum.2023-0698

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