Fibromyalgia & musculoskeletal pain
Effects of exercise-based interventions on inflammatory markers in patients with fibromyalgia: A systematic review and meta-analysis
Pooled result · Pro-inflammatory biomarkers (19 comparisons)Result — go to the resultSMD 1.74 95 % CI 0.85–2.62Authors' conclusion
EBIs are effective in inducing an immunomodulatory response in FM, characterized by decreased pro-inflammatory signaling. However, there was no evidence of an increase in anti-inflammatory biomarkers.
Study context
- Population
- Patients with fibromyalgia (FM)11 studies
- Comparison
- Exercise-based interventions in FM
- Outcome
- Pro-inflammatory and anti-inflammatory biomarkers
Methodological detailsCochrane Risk of Bias Tool, GRADE
- Cochrane Risk of Bias Tool
- GRADE
Pooled result
Pro-inflammatory biomarkers (19 comparisons)
SMD
1.74
95 % CI 0.85–2.62
P < 0.05
EBIs
SMD 1.74 (95 % CI 0.85–2.62); P < 0.05
As reported in the abstract
Further pooled results
Anti-inflammatory biomarkers (IL10), 6 comparisons
- No statistically significant increase by EBIs; very low certainty of evidence
Type and modality of exercise
- Evidence for acute and maintained effects; aerobic and aquatic modalities better than resistance exercise
Original publication
Effects of exercise-based interventions on inflammatory markers in patients with fibromyalgia: A systematic review and meta-analysis. Semin Arthritis Rheum. Published 13 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →