Pain‐Related Risk Factors Among Radiologic Stages of Knee Osteoarthritis: Data From the Osteoarthritis Initiative
Authors' conclusion
Multiple factors are associated with pain in patients with knee OA. As the disease progresses, the number of significant risk factors gradually reduces.
Study context
- Population
- Osteoarthritis Initiative individuals with baseline K/L grade and numerical rating scale (NRS) pain data, knee osteoarthritis (OA) stratified into 4 K/L categories
- Participants
- 4,446 individuals
- Exposure
- No pain vs Mild pain vs Moderate/severe pain
- No painn = 1,574
- Mild painn = 1,138
- Moderate/severe painn = 1,734
- Outcome
- Pain-related risk factors (pain severity by NRS: no, mild, moderate/severe) across K/L stages of knee OA
- Follow-up
- Baseline
Methodological detailsgeneralized ordinal logistic regression, stratified by K/L grade
- Generalized ordinal logistic regression
- Stratified by K/L grade
Main finding
As reported in the abstract
Pain risk factors (entire population and premorbid-stage subgroup)
Observational data: associations, not effects.
Original publication
Pain‐Related Risk Factors Among Radiologic Stages of Knee Osteoarthritis: Data From the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). Published 18 January 2023. doi:10.
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