Osteoporosis & bone health

Outcome evaluation of osteoporosis patient education: an observational study comparing an intervention group and matched control group

Osteoporos IntPublished Observational matched cohort study

Main finding · Quality of life, physical component scoreResult — go to the resultDifference −1.28 95% CI −2.29 to −0.28

Authors' conclusion

Our findings show that citizens who participated in patient education were more adherent to medication. Results related to quality of life, physical activity, and fear of falling were inconclusive, and therefore, we cannot draw conclusions regarding the overall effectiveness of osteoporosis patient education.

Study context

Population
Citizens with osteoporosis in 15 Danish municipalities; assessed on average 3.7 years after patient education1,660 answered questionnaire
Participants
3,132 participants
Exposure
Osteoporosis patient education vs no patient education
Outcome
Two primary outcomes: fractures and quality of life
Follow-up
On average 3.7 years after participation
Methodological detailsmatched (1:1) on gender, age, time of osteoporosis diagnosis and type of previous osteoporotic fractures, 15 Danish municipalities, logistic or linear regression
  • Matched (1:1) on gender, age, time of osteoporosis diagnosis and type of previous osteoporotic fractures
  • 15 Danish municipalities
  • Logistic or linear regression

Main finding

Quality of life, physical component score

Difference

−1.28

95% CI −2.29 to −0.28

Participantsvs Controls
difference −1.28 (95% CI −2.29 to −0.28)

As reported in the abstract

Observational data: associations, not effects.

Secondary outcomes

OutcomeOR (95% CI)
Worry about fallingParticipants more worried1.61 (1.31–1.99)
Active spare timeParticipants had more active spare time0.59 (0.44–0.81)
Adherence to medicationParticipants more adherent1.74 (1.49–2.03)
OutcomeDifference (95% CI)
Bone-specific physical activitiesParticipants performed more0.50 (0.01–0.99)

Original publication

Outcome evaluation of osteoporosis patient education: an observational study comparing an intervention group and matched control group. Osteoporos Int. Published 1 December 2025. doi:10.1007/s00198-025-07785-7

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