Osteoporosis & bone health

Osteoporosis management in adults with schizophrenia following index hip fracture event: a 10-year population-based retrospective cohort study, Ontario, Canada

Osteoporos IntPublished Retrospective cohort study

Main finding · Osteoporosis testing or treatment (composite)Result — go to the resultEstimate 0.795 CI 0.721–0.877

Authors' conclusion

In this population-based retrospective cohort study, a schizophrenia diagnosis among hip fracture patients was associated with a lower incidence of testing or treatment, after accounting for mortality, and several enabling and predisposing factors.

Study context

Population
Individuals aged 66–105 years with index hip fracture between fiscal years 2009 and 2018, Ontario, Canada1,890 (3.6%) with schizophrenia
Participants
52,722 individuals
Exposure
Hip fracture patients with vs without schizophrenia
  • Schizophrenian = 1,890
Outcome
Composite of:
  • Pharmacologic prescription for osteoporosis
  • A bone mineral density (BMD) test
Methodological detailspopulation-based, health administrative databases, Fine-Gray subdistribution hazard regression, mortality as competing event
  • Population-based
  • Health administrative databases
  • Fine-Gray subdistribution hazard regression, mortality as competing event

Main finding

Osteoporosis testing or treatment (composite)

Estimate

0.795

CI 0.721–0.877

As reported in the abstract

Observational data: associations, not effects.

Further findings

Long-term care residents

standardized difference 0.59

Frail

standardized difference 0.54

Without a primary care provider

standardized difference 0.18

Original publication

Osteoporosis management in adults with schizophrenia following index hip fracture event: a 10-year population-based retrospective cohort study, Ontario, Canada. Osteoporos Int. Published 17 May 2024. doi:10.1007/s00198-024-07123-3

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