Characterization of Hip Fractures Among Adults With Schizophrenia in Ontario, Canada
Authors' conclusion
The findings of this cross-sectional study suggest that individuals with schizophrenia experience an earlier age of onset and considerably higher rate of hip fractures compared with the general population
Study context
- Population
- Patients aged 40 to 105 years with hip fracture-related hospitalization, Ontario, Canada, April 1, 2009–March 31, 2019
- Participants
- 109,908 patients
- Exposure
- Adults with schizophrenia vs without schizophrenia
- Schizophrenian = 4,251
- Without schizophrenian = 105,657reference
- Outcome
- Sex-specific age-standardized annual hip fracture rate per 10 000 individuals and annual percent change in age-standardized rates
Methodological detailsindividually linked health administrative databases, age-standardized to 2011 Ontario population, joinpoint regression
- Individually linked health administrative databases
- Age-standardized to 2011 Ontario population
- Joinpoint regression
Main finding
As reported in the abstract
Age-standardized hip fracture rate per 10 000 individuals, overall
- Annual decrease in age-standardized rates in both groups (joinpoint regression), 95% CI −1.1% to −0.3%
- 0.7%
Observational data: associations, not effects.
Further findings
Frailty
standardized difference 0.40
Previous fragility fractures
standardized difference 0.11
Annual percent change in age-standardized hip fracture rates (both groups)
- Steady annual decrease (joinpoint regression), 95% CI −1.1% to −0.3%
- 0.7%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Characterization of Hip Fractures Among Adults With Schizophrenia in Ontario, Canada. JAMA Netw Open. Published 3 April 2023. doi:10.
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