Claims-based frailty index and risk of hospitalisation for hip fracture among adults aged 60–74 years in Tokyo, Japan
Authors' conclusion
The CFI can help identify individuals who may benefit from targeted interventions to prevent hip fractures.
Study context
- Population
- National Health Insurance beneficiaries aged 60–74 years with an annual health checkup April 2017–March 2018, Tokyo, Japan
- Participants
- 606,449 beneficiaries
- Exposure
- Pre-frail and frail vs robust by claims-based frailty index
- Robustn = 553,747reference
- Pre-frailn = 47,348
- Frailn = 5,354
- Outcome
- Hospitalisation for hip fractures
- Follow-up
- Through March 2023
Methodological detailslinked health checkup and medical claims data, Cox proportional hazards models
- Linked health checkup and medical claims data
- Cox proportional hazards models
Main finding
As reported in the abstract
Hazard ratio
2.17
95% CI 1.87–2.51
Pre-frail
Hazard ratio
3.50
95% CI 2.62–4.69
Frail
Observational data: associations, not effects.
Further findings
Discrimination (Harrell's C-statistic) with vs without CFI
- The CFI modestly improved discrimination beyond FRAX-related variates
Original publication
Claims-based frailty index and risk of hospitalisation for hip fracture among adults aged 60–74 years in Tokyo, Japan. Osteoporos Int. Published 1 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →