Osteoporosis & bone health

Osteoporosis and fracture risk assessment in adults with ischaemic stroke

Osteoporos IntPublished Observational cohort study

Authors' conclusion

This study found that a simple bedside tool, the FRAC-stroke score, can predict fracture after ischaemic stroke.

Study context

Population
Adults aged ≥ 50 years admitted with ischaemic stroke over a 12-month period (2020), telephone interview one-year post-strokeconsented to interview
Participants
131 adults
Outcome
Prevalence of osteoporosis, falls and fractures
Follow-up
One-year post-stroke

Main finding

As reported in the abstract

12 months post-stroke

Minimal trauma fracture in the 12 months post-stroke (6 female)

Eleven (8.4%)

FRAC-stroke score ≥ 15 (≥ 5% risk of fracture in the year after stroke)

34

25.9%

Falls pre- vs post-stroke

19.8% vs 31.3%

p = 0.04

Observational data: associations, not effects.

Further findings

FRAC-stroke score, fracture vs no fracture post stroke

FRAC-stroke score higher with fracture than without
20.4 vs 8.9, p < 0.001

FRAC-stroke score for predicting fracture (ROC)

AUC
0.867 (95% CI 0.785-0.949, p < 0.005)
Optimal cutoff
12
Sensitivity at cutoff 12
90.9%
Specificity at cutoff 12
70%

Original publication

Osteoporosis and fracture risk assessment in adults with ischaemic stroke. Osteoporos Int. Published 4 May 2024. doi:10.1007/s00198-024-07099-0

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