Obesity is an independent risk factor for cancer development following diagnosis of dermatomyositis
Main finding · Subsequent cancer diagnosis (any obesity code)Result — go to the resultOdds ratio 1.98 95% CI 1.70–2.30Study context
- Population
- Patients with dermatomyositis (DM)6,055 with BMI data
- Participants
- 12,722 patients
- Exposure
- DM with obesity vs DM without obesity
- Outcome
- Subsequent cancer diagnosis
Methodological detailslogistic regression adjusted for age and sex, time to event analysis
- Logistic regression adjusted for age and sex
- Time to event analysis
Main finding
Subsequent cancer diagnosis (any obesity code)
Odds ratio
1.98
95% CI 1.70–2.30
Obesevs Not obese
OR 1.98 (95% CI 1.70–2.30)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Estimate | |
|---|---|---|
| Cancer, BMI subgroup (BMI ≥30 vs <30 kg/m²) | OR 1.23 (CI 1.02–1.49) | |
| Cancer, time to event analysis (any obesity code)16 % increased hazard | aHR 1.16 (95% CI 1.02–1.31) | |
| 0.512Ratio (log scale) |
Cancer types
- Most frequent cancer overall was breast cancer; DM with obesity had higher frequencies of lymphoma, colorectal, melanoma, uterine, renal cancers vs DM without obesity
Original publication
Obesity is an independent risk factor for cancer development following diagnosis of dermatomyositis. Semin Arthritis Rheum. Published 4 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →