Non-osteoporotic fractures are associated with increased risk of subsequent major osteoporotic fractures
Authors' conclusion
Non-osteoporotic fractures are significantly associated with increased risk for future major osteoporotic fractures relative to the general population, yet to a lesser extent compared to major and minor osteoporotic fractures.
Study context
- Population
- Patients in UK primary care electronic health recordsUK primary care health records
- Participants
- 39,931 / 19,397 / 50,115 / 1,951,388
- Exposure
- Prior major, minor or non-osteoporotic fracture vs general population
- Major osteoporotic fracturen = 39,931
- Minor osteoporotic fracturen = 19,397
- Non-osteoporotic fracturen = 50,115
- General populationn = 1,951,388reference
- Outcome
- Incident major osteoporotic fractures following the index date
Methodological detailsUK primary care electronic health records
- UK primary care electronic health records
Main finding
As reported in the abstract
Future major osteoporotic fractures
Each group vs general populationStandardized incidence rate ratio (95% CI)
Major osteoporotic fracture
2.73(2.64–2.82)
Minor osteoporotic fracture
2.43(2.32–2.54)
Non-osteoporotic fracture
1.83(1.74–1.92)
Observational data: associations, not effects.
Original publication
Non-osteoporotic fractures are associated with increased risk of subsequent major osteoporotic fractures. Osteoporos Int. Published 13 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →