Fibromyalgia & musculoskeletal pain

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study

Arthritis Care Res (Hoboken)Published Prospective cohort study

Authors' conclusion

This study provides the largest prospective data to date to support exposure to the stress of deployment to a warzone as a significant factor related to the onset of fibromyalgia.

Study context

Population
US military service members assessed before and upon return from combat deployment
Participants
1,761 members
Exposure
Pre-deployment vs post-deployment
Outcome
Fibromyalgia (2011 questionnaire modification of the 2010 ACR preliminary diagnostic criteria)
Follow-up
Upon return from combat deployment
Methodological detailslongitudinal, pre- and post-deployment assessment
  • Longitudinal
  • Pre- and post-deployment assessment

Main finding

As reported in the abstract

Prevalence of fibromyalgia (2011 modification of 2010 ACR preliminary criteria) · Predeployment and post deployment

P < 0.001

Observational data: associations, not effects.

Further findings

Prevalence of PTSD symptoms (PTSD Checklist Stressor-Specific Version) · increased slightly

P > 0.05

Men

Women

OutcomeOR
Developing FM post deployment, by PTSD predeployment2.96
Developing PTSD post deployment, by FM predeployment3.12

Original publication

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study. Arthritis Care Res (Hoboken). Published 9 February 2026. doi:10.1002/acr.80008

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