National burden of rheumatoid arthritis in Canada, 1990–2019: findings from the Global Burden of Disease Study 2019 – a GBD collaborator-led study
Authors' conclusion
Trends in RA burden indicators over time and differences by age and sex have important implications for Canadian policy-makers, researchers and care providers.
Study context
- Population
- Rheumatoid arthritis (RA) burden in Canada, 1990–2019, GBD data
- Comparison
- Canada vs countries with similarly high Socio-Demographic Index values and global rates
- Outcome
- RA burden indicators: prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs) and DALYs, and their trends
- Follow-up
- 1990 to 2019
Methodological detailsGlobal Burden of Disease Study 2019 analysis, Bayesian meta-regression, cause of death ensemble model, age standardised
- Global Burden of Disease Study 2019 analysis
- Bayesian meta-regression
- Cause of death ensemble model
- Age standardised
Main finding
As reported in the abstract
Change in age-standardised RA burden indicators in Canada · 1990–2019
- Prevalence rate increase
- 27%
- Mortality rate decrease
- 27%
- YLL rate decrease
- 30%
- YLD increase
- 27%
- DALY rate increase
- 13%
Further findings
Timing of decline in mortality and YLL rates
- Decline especially pronounced after 2002
Sex and age differences
- Burden higher in females for all indicators
- DALY rates higher among older age groups, peaking at age 75-79 years
Canada vs global
- Prevalence and disability-adjusted life-years (DALYs) higher in Canada than global rates
Original publication
National burden of rheumatoid arthritis in Canada, 1990–2019: findings from the Global Burden of Disease Study 2019 – a GBD collaborator-led study. RMD Open. Published 12 January 2024. doi:10.
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