Myocardial dysfunction is linked to endothelial dysfunction in JIA patients: a study of novel aortic circumferential strain
Authors' conclusion
We believe that this study adds more evidence to the latter.
Study context
- Population
- Patients with JIA and controls
- Comparison
- JIA vs controls
- JIAn = 22
- Outcome
- Correlation between extent of vascular (FMD, ACS) and myocardial (3D speckle tracking echocardiography, GLS) involvement
Main finding
As reported in the abstract
Correlation between ACS and GLS
- Significant correlation between ACS and global longitudinal strain (GLS)
Observational data: associations, not effects.
Further findings
| Outcome | JIAMedian | Controls |
|---|---|---|
| ACS and FMD | 15 | median 21 |
| GLS | 17 | 22 |
ACS and flow-mediated dilation (FMD)
- Both ACS and FMD impaired in cases vs controls
GLS
- GLS significantly reduced in cases vs controls
Vascular relaxibility and JADAS
- Impaired vascular relaxibility associated with increased JADAS scores
Original publication
Myocardial dysfunction is linked to endothelial dysfunction in JIA patients: a study of novel aortic circumferential strain. Pediatr Rheumatol Online J. Published 25 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →