How early is early for juvenile idiopathic arthritis (JIA)? Insights from the infantile-onset juvenile idiopathic arthritis patients of the PERA research group cohort
Authors' conclusion
This study suggests that patients with infantile-onset JIA exhibit distinct characteristics regarding JIA category, joint involvement and uveitis development
Study context
- Population
- Patients with JIA with symptom onset before age 2 (infantile-onset JIA), PERA research group cohort
- Participants
- 199 patients
- Exposure
- Symptom onset ≤12 months vs >12 months
- Outcome
- Clinical, laboratory and outcome characteristics of infantile-onset JIA
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
- Median age at symptom onset
- 17 months
- Median age at diagnosis
- 20 months
- Persistent oligoarticular JIA
- 59.8%
- Systemic JIA
- 13.6%
- Rheumatoid factor (RF)-negative polyarticular JIA
- 11.6%
Observational data: associations, not effects.
Further findings
Remission at last visit
- In remission with medication
- 59.8%
- In remission without medication
- 18.1%
Original publication
How early is early for JIA? Insights from the infantile-onset juvenile idiopathic arthritis patients of the PERA research group cohort. Rheumatology (Oxford). Published 14 August 2025. doi:10.
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