Musculoskeletal Ultrasound and the Assessment of Disease Activity in Juvenile Idiopathic Arthritis
Authors' conclusion
Subclinical synovitis was commonly observed in this cohort of JIA patients.
Study context
- Population
- Juvenile idiopathic arthritis (JIA) patients with an active joint count of >4
- Participants
- 30 patients
- Outcome
- Frequency of subclinical synovitis (synovitis detected by MSUS only)
Methodological details42-joint musculoskeletal ultrasonography (MSUS) at baseline and 3 months, generalized estimation equations, Spearman's correlation
- 42-joint MSUS at baseline and 3 months
- Generalized estimation equations
- Spearman's correlation
Main finding
As reported in the abstract
Subclinical synovitis on MSUS
Joints with subclinical synovitis
30%
Observational data: associations, not effects.
Further findings
Clinical arthritis vs MSUS synovitis
- Clinical arthritis of fingers, wrists and knees significantly associated with MSUS synovitis in these joints
Correlation of MSUS synovitis with PtGA
- Rs (moderate), P = 0.014
- 0.44
Correlation of MSUS synovitis with Childhood Health Assessment Questionnaire (C-HAQ)
- Rs (weak), P = 0.045
- 0.37
Correlation of MSUS synovitis with PhGA · follow-up visit
- Rs (strong), P = 0.001
- 0.61
Correlation of MSUS synovitis with active joint count (AJC) · follow-up visit
- Rs (weak), P = 0.048
- 0.37
Original publication
Musculoskeletal Ultrasound and the Assessment of Disease Activity in Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). Published 21 February 2023. doi:10.
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