Osteoporosis & bone health

Mental disorders and osteoporosis treatment in patients with hip fracture—a Danish population-based cohort study

Osteoporos IntPublished Population-based cohort study

Authors' conclusion

AOM initiation following hip fracture remains suboptimal. Patients with mental disorders were less likely to initiate AOM after hip fracture, highlighting a persistent gap in secondary fracture prevention among vulnerable populations.

Study context

Population
Patients aged ≥ 65 with first-time hip fracture 2010–2020 and no recent anti-osteoporosis medication (AOM) use, Danish medical registries
Participants
57,887 patients
Exposure
Mental disorder categories vs no mental disorder
Outcome
Cumulative incidence of AOM initiation (pharmacy dispensations and hospital treatment codes), death as a competing risk
Follow-up
1 year
Methodological detailsregistry-based, death as a competing risk
  • Registry-based
  • Death as a competing risk

Main finding

As reported in the abstract

AOM initiation after hip fracture, cumulative incidence functions (CIF)

Observational data: associations, not effects.

Further findings

AOM initiation by subgroup

Higher initiation in patients < 80 years, females, with previous fractures, less somatic comorbidity, no other mental comorbidities, cohabiting in own home, and more recent calendar years

Original publication

Mental disorders and osteoporosis treatment in patients with hip fracture—a Danish population-based cohort study. Osteoporos Int. Published 9 April 2026. doi:10.1007/s00198-026-07975-x

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