Spondyloarthritis & psoriatic arthritis

Management of Peripheral Arthritis in Patients With Psoriatic Arthritis: An Updated Literature Review Informing the 2021 Group in Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) Treatment Recommendations

J RheumatolPublished Systematic literature review informing treatment recommendations

An erratum to this article was published (J Rheumatol, Dec 2022 ↗)

Methodological detailsGRADE-informed approach, consensus meetings, RCTs from February 19, 2013, to August 28, 2020 reviewed, Working group of clinicians and patient research partners
  • GRADE-informed approach
  • Consensus meetings
  • RCTs from February 19, 2013, to August 28, 2020 reviewed
  • Working group of clinicians and patient research partners

Recommendations

As issued by the authors

  1. strongly recommends

    Treatment-naïve: Conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) (MTX, SSZ, LEF) and phosphodiesterase 4 inhibitors, with regular assessment and early escalation to achieve treatment target

  2. strongly recommended

    Treatment-naïve: bDMARDs (TNFi, IL-17i, IL-12/23i, IL-23i) and Janus kinase inhibitors (JAKi)

  3. strongly recommend

    Inadequate response to csDMARDs: TNFi, IL-17i, IL-12/23i, IL-23i and JAKi

  4. strongly recommend

    Prior bDMARD experience: a second TNFi, IL-17i, IL-23i and JAKi

  5. conditionally recommends

    Adequate physical activity, smoking cessation and diet to control weight gain (evidence for nonpharmacological interventions very low)

Original publication

Management of Peripheral Arthritis in Patients With Psoriatic Arthritis: An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations. J Rheumatol. Published 15 October 2022. doi:10.3899/jrheum.220315

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