Long‐Term Mortality Following SARS‐CoV‐2 Infection in Rural Versus Urban Dwellers With Autoimmune or Inflammatory Rheumatic Disease: A Retrospective Cohort Analysis From the National COVID Cohort Collaborative
Main finding · Two-year all-cause mortalityResult — go to the resultAdjusted hazard ratio 1.24 95% CI 1.19–1.29Authors' conclusion
Rural residence in people with AIRD was independently associated with higher two-year post-COVID-19 mortality in a large US cohort after adjusting for background risk factors.
Study context
- Population
- Adults with two or more AIRD diagnostic codes and a COVID-19 diagnosis documented between April 2020 and March 2023, National COVID Cohort Collaborative (US)
- Participants
- 86,467 adults
- Exposure
- Rural vs urban dwellers with AIRD after SARS-CoV-2 infection
- Outcome
- All-cause mortality
- Follow-up
- Up to two years
Methodological detailsmultivariable Cox proportional hazards, inverse probability treatment weighting
- Multivariable Cox proportional hazards
- Inverse probability treatment weighting
Main finding
Two-year all-cause mortality
Adjusted hazard ratio
1.24
95% CI 1.19–1.29
Ruralvs Urban
aHR 1.24 (95% CI 1.19–1.29)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Two-year post-COVID-19 mortality by medication · up to two years
- GC, immunosuppressive and RTX prescriptions associated with higher risk
- Nonbiologic or biologic DMARDs associated with lower risk
Original publication
Long‐Term Mortality Following SARS‐CoV‐2 Infection in Rural Versus Urban Dwellers With Autoimmune or Inflammatory Rheumatic Disease: A Retrospective Cohort Analysis From the National COVID Cohort Collaborative. Arthritis Care Res (Hoboken). Published 16 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →