Systematic screening for multimorbidities in patients with inflammatory rheumatic diseases enhanced preventive medication use and reduced hospitalisations: an exposed-non-exposed study
Main finding · Meeting the PE (multivariate analysis)Result — go to the resultAdjusted odds ratio 1.6 CI 1.2–2.2Authors' conclusion
Systematic multimorbidity screening in patients with IRD boosted preventive medication use and reduced hospital admissions
Study context
- Population
- Patients with chronic inflammatory rheumatic diseases (IRD) in the French national health database
- Participants
- 286 vs 858
- Exposure
- Systematic multimorbidity screening programme vs no screening
- Exposedn = 286
- Controlsn = 858reference
- Outcome
- Composite score of dispensation of multimorbidity-preventing drugs:
- Vaccines
- Lipid-lowering agents
- Antiosteoporotic medications
- Antiplatelet drugs
- Follow-up
- Year following the index date
Methodological detailsFrench national health database, matched controls, multivariate analysis, propensity score matching
- French national health database
- Matched controls
- Multivariate analysis
- Propensity score matching
Main finding
Meeting the PE (multivariate analysis)
Adjusted odds ratio
1.6
CI 1.2–2.2
P < 0.01
As reported in the abstract
Observational data: associations, not effects.
Further findings
Meeting the PE (propensity score matched analysis) · year following the index date
OR 1.5 · P = 0.015
Emergency admission and hospitalisations for fracture, cardiovascular events or infection · propensity score matched
OR 0.42 · P < 0.01
Severe infections · propensity score matched
P = 0.03
- Meeting the primary endpoint (PE) (propensity score matched analysis): propensity score matched: 281 exposed and 281 controls
Meeting the PE (propensity score matched analysis) · year following the index date
- Increased utilisation of vaccines, cholesterol-lowering drugs and antiosteoporotic medications
Original publication
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